Molecular Phenotypes
of Null Alleles in Cells
A program to better understand the function of every human gene and generate a catalogue of the molecular and cellular consequences of inactivating genes.
gene list
Phase 1 will focus on 1,000 protein-coding genes, exploring different ways to knock out gene function.
data Catalogue
The first MorPhic Public Data Release includes the first 11 studies generated by the consortium.
About the MorPhiC Program
The MorPhiC program aims to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene by using in-vitro multicellular systems. The catalog will be made available for broad use by the biomedical community. The program will start with a Phase 1 to optimize available methods to create null alleles and measure their phenotypic effects in a target subset of 1,000 protein coding genes across the program.
Learn more about the MorPhiC program →
Frequently asked questions
Policies
The following policies were approved by the MorPhiC Steering Committee: