Molecular Phenotypes
of Null Alleles in Cells
A program to better understand the function of every human gene and generate a catalogue of the molecular and cellular consequences of inactivating genes.
gene list
Phase 1 will focus on 1,000 protein-coding genes, exploring different ways to knock out gene function.
About the MorPhiC Program
The MorPhiC program aims to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene by using in-vitro multicellular systems. The catalog will be made available for broad use by the biomedical community. The program will start with a Phase 1 to optimize available methods to create null alleles and measure their phenotypic effects in a target subset of 1,000 protein coding genes across the program.
Learn more about the MorPhiC program →
Frequently asked questions
Policies
The following policies were approved by the MorPhiC Steering Committee: